B12 Methylcobalamin · 5000 mcg
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Vitamin B12 is the cofactor of enzymatic reactions with various physiological functions. It is necessary for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted to S-adenosylmethionine. B12 deficiency leads to deficiencies in these two pathways, disrupting neurological function, including poor formation of myelin sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.
Methylcobalamin, the major circulating form of B12 and the one that is transported to peripheral tissues, has been shown to reduce not only homocysteine, but also inflammatory factors and carotid artery plaque volume in patients with suffered a stroke, as well as pain and neuropathy in diabetics. Due to its relationship with myelin production and neurological function, high dose B12 has been used in various neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.
Some people, especially those with malabsorption or low dietary intake, are at greater risk of B12 deficiency. People with poor B12 absorption rely on passive absorption, which is typically 1% of the amount ingested. Therefore, high doses may be necessary for people with higher B12 needs, such as the elderly and those with neurodegenerative disorders.
Adults: 1 tablet per day or as recommended by a healthcare professional. Dissolve under the tongue. Consult a health care practitioner for use beyond 4 months.
Medicinal ingredients: Vitamin B12 (Methylcobalamin) 5000 mcg
Nonmedicinal ingredients: Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, vegetable grade magnesium stearate (lubricant).
You have questions ?
You can reach our team of experts by telephone Monday to Friday from 10 a.m. to 5 p.m. We will be able to help you choose the right product for you.