Cortisolv
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Cortisolv is a multi-functional herbal supplement that offers significant and complementary benefits for people seeking help in coping with daily stress. It contains a unique combination of clinically tested and patented ingredients, including Relora®, Sensoril® and Suntheanine®, as well as banaba leaf and maral extracts. Together, these herbs help the overburdened body and mind work towards their normal state of balance and resolve many of the biochemical changes that occur as a result of repeated and frequent exposure to stressors and cortisol.
Relora® is a proprietary, patented blend of Magnolia officinalis and Phellodendron amurense bark extracts standardized to honokiol and berberine respectively. These herbs have a history of traditional use in the treatment of stress and occasional feelings of anxiety. In modern times, they and their active ingredients (honokiol and berberine) are used to promote relaxation and reduce perceived stress and stress-related eating. Studies on rodent stress show a reduction in induced feelings of anxiety. Human studies show positive changes in DHEA (dehydroepiandrosterone) and cortisol levels, less weight gain (compared to controls) and reductions in perceived stress and transient feelings of anxiety in subjects taking Relora (500 mg to 750 mg for four to six weeks). For example, cortisol exposure and psychological mood states were studied in 56 subjects (35 men and women) taking Relora (250 mg twice daily) or placebo. After four weeks of supplementation, salivary cortisol exposure was significantly lower (-18%) in the Relora group compared to placebo. The Relora group also had significantly better mood state parameters, including lower indices of overall stress (-11%), tension (-13%), anger (-42%), occasional fatigue (-31%), and confusion (-27%), and higher indices of overall mood state (+11%) and vigor (+18%).
Sensoril® is an optimized extract of ashwagandha (Withania somnifera) root and leaf that represents a major advance in ashwagandha preparations. Sensoril's proprietary and patented extraction process produces very high and potent levels of ashwagandha's bioactive constituents that combat stress and improve cognition. In fact, Sensoril is standardized to a minimum of 10% glycowithanolides. Sensoril's excellent safety record is one of the most comprehensive of all ashwagandha ingredients sold.
Ashwagandha has been revered as an adaptogen for thousands of years. It is used to balance, energize and revitalize the body and for its value as a cognitive enhancer. Sensoril has multiple health benefits and its superior efficacy has been demonstrated in randomized, double-blind, placebo-controlled human clinical trials. Results from these trials revealed that Sensoril, taken at doses of 500 to 1000 mg/d, supported healthy cortisol and DHEA levels; improved working memory, reaction time and cognitive ability; improved auditory-verbal working memory; improved negative changes in cardiovascular parameters associated with mental stress; and improved endothelial function and glucose and lipid metabolism.
Suntheanine® is a pure form of L-theanine that is produced via a proprietary fermentation process, resulting in 100% pure L-isomer-theanine. Clinical research suggests that 50 to 200 mg/d of Suntheanine naturally stimulates activity in the brain called alpha waves, which are associated with a relaxed but alert mental state. L-theanine has had significant anti-stress effects on laboratory animals under psychosocial stress. In humans, similar results were observed in which L-theanine helped the body resist the biochemical changes associated with stress. given to boys aged 8-12 years, improved aspects of sleep quality, including significantly higher sleep percentage and sleep efficiency scores, as well as a non-significant trend toward decreased activity during sleep.
Banaba leaf (Lagerstroemia speciosa) has long been used in traditional medicine, particularly in Southeast Asia, as a glucose modulator. More recently, animal and human research on banaba leaf and its active ingredients, including corosolic acid, suggest multiple mechanisms that influence glucose and lipid metabolism. In addition, corosolic acid inhibits the enzyme that facilitates the conversion of cortisone to cortisol. Maral extract (Rhaponticum carthamoides) has been widely used in traditional Siberian medicine, primarily to treat overwork and common weakness resulting from illness. It has also been used historically as a stimulant and remedy to support male sexual function.
The main bioactive constituents of this plant are ecdysteroids, flavonoids and phenolic acids. A review of marine chemistry and pharmacology calls it an "adaptogenic herbal remedy."
Adults: Take one capsule twice daily or as directed by your healthcare professional. Consult a health care practitioner for use beyond two weeks.
Medicinal ingredients (per capsule):
Relora® (a proprietary blend of a patented extract from Magnolia officinalis bark and a proprietary extract from Phellodendron amurense bark)(8.5% Honokiol; 2.5% Berberine) ...... 250 mg
Sensoril® Ashwagandha (Withania somnifera) Root and Leaf Extract (32% Withania oligosaccharides; 10% withanolides) ...... 150 mg
Suntheanine® L-Theanine ...... 100 mg
Banaba Leaf Extract (Lagerstroemia speciosa)(1% corosolic acid) ...... 48 mg
Maral Extract (Rhaponticum carthamoides)(root) ...... 50 mg
Non-medicinal ingredients: HPMC (capsule), L-leucine, ascorbyl palmitate, medium-chain triglyceride oil, silica, microcrystalline cellulose.
You have questions ?
You can reach our team of experts by telephone Monday to Friday from 10 a.m. to 5 p.m. We will be able to help you choose the right product for you.