CoQ10 plays a beneficial role in the treatment of various chronic disorders characterized by impaired mitochondrial bioenergetics and/or increased oxidative stress, such as heart failure, Parkinson's disease, and migraine. R-alpha-lipoic acid may have greater bioavailability than the synthetic mixture. In vivo studies have shown that combinations of CLA and R-alpha-lipoic acid act synergistically to prevent mitochondrial degradation. Standardized Ginkgo biloba extract supports cognitive functioning, neuropsychiatric symptoms, and functional abilities in individuals with vascular dementia and Alzheimer's dementia. Resveratrol, a potent antioxidant found in Japanese knotweed, improves muscle mitochondrial respiration in obese individuals, as well as several cardiometabolic risk factors. Clinical trials indicate that administration of grape seed proanthocyanidins stimulates mitochondrial function in muscle skeletal structure of obese Zucker rats and improves cognitive function in older adults.Suitable for vegetarians/vegansOxidative damage to mitochondria is a major factor in cellular aging, as well as neurological decline. While lifestyle interventions such as calorie restriction help improve mitochondrial function in young, non-obese adults, certain supplements such as L-carnitine also have therapeutic benefits. The salt of L-carnitine, called acetyl-L-carnitine (ALC), is the preferred form in disease and aging because it is better absorbed and easily crosses the blood-brain barrier. ALC has been shown not only to improve mood but also to play an important role in disorders of aging, including fatigue, hypertension, insulin resistance, diabetic neuropathy, and dementia. Mito AMP also contains Ginkgo biloba extract, resveratrol, R-alpha-lipoic acid, and grape seed proanthocyanidins, all of which modulate mitochondrial function, improve cognitive function, and/or reduce inflammation associated with cognitive decline. Pyrroloquinoline quinone (PQQ) plays a key role in mitochondrial biogenesis through cellular signaling (PGC-1 alpha). Clinical trials have shown improved cerebral blood flow and brain function, improved memory when combined with CoQ10, as well as increased vigor and a significant reduction in symptoms of fatigue, tension, low mood, and confusion.
Adults: 1 capsule 3 times daily with food or as directed by a health care practitioner. Consult a health care practitioner for use beyond 4 weeks.
Medicinal Ingredients: Acetylcarnitine (N-acetyl-L-carnitine hydrochloride) 300 mg Ginkgo Biloba Extract (Ginkgo biloba) (leaf) (24% Flavone Glycosides, 6% Terpene Lactones) 80 mg Japanese Knotweed Extract (Polygonum cuspidatum) (root) (20% Trans-Resveratrol) 66.67 mg Coenzyme Q10 (microorganism) 60 mg R-Alpha-Lipoic Acid 50 mg Grape Seed Extract (Vitis vinifera) (seed) (80% Oligomeric Proanthocyanidins) 30 mg BioPQQ® (pyrroloquinoline quinone disodium salt) 3.33 mg Non-medicinal Ingredients: Vegetable capsule (carbohydrate gum [cellulose], purified water), silica, Vegetable grade magnesium stearate (lubricant), microcrystalline cellulose.
