Bromelain
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Bromelain, found in pineapple stems, is a combination of several proteolytic enzymes classified as cysteine or thiol proteinases. Bromelain's long history as a digestive aid is partly attributed to its ability to digest proteins over a wide pH range. However, it has also been shown to stimulate pancreatic enzyme production and improve epithelial integrity in experimental models.1
In addition to its function as a digestive enzyme, bromelain is absorbed in the digestive tract and retains its enzymatic activity in the blood. Among its many enzymatic effects, bromelain has been shown to be a potent anti-inflammatory agent, reducing levels of inflammatory signals, such as tumor necrosis factor (TNF) and nuclear factor kappa B (NF-kappaB).
The anti-inflammatory, fibrinolytic and analgesic effects of bromelain are also responsible for many of its beneficial effects on the musculoskeletal system. In an open trial, bromelain supplementation was shown to reduce acute knee pain as well as stiffness and function, with a dose-dependent effect. In another clinical trial for mild/moderate knee osteoarthritis, bromelain had similar effectiveness to standard treatment after four weeks. Faster recovery and reduction in pain and swelling following several types of minor trauma have also been reported with bromelain.
Adults: 1 capsule daily with food or as directed by a health care practitioner. Consult a health care practitioner for prolonged use.
Medicinal ingredients: Bromelain (Ananas comosus var. comosus) (stem) 7,500,000 FCC PU (500 mg)
Nonmedicinal ingredients: Gelatin capsule (gelatin, purified water), vegetable grade magnesium stearate (lubricant).
You have questions ?
You can reach our team of experts by telephone Monday to Friday from 10 a.m. to 5 p.m. We will be able to help you choose the right product for you.