Bio B12 + Folic Acid

High-dose B12 formula with folic acidHelps prevent vitamin B12 deficiencyContributes to red blood cell formationHelps the body metabolize carbohydrates, fats, and proteinsHelps reduce the risk of neural tube defects when taken before and during the early stages of pregnancyProvides 1000 mcg of vitamin B12 and 400 mcg of folic acid per doseBio B12 + Folic Acid includes a high dose of vitamin B12 to support macronutrient metabolism and prevent vitamin B12 deficiency. Vitamin B12 is an important cofactor in two enzymatic reactions: 1 methylmalonyl-CoA mutase, which helps dissolve branched-chain amino acids and irregular-chain fatty acids; 2 methionine synthase, which is necessary for methyl transfer reactions, including the conversion of homocysteine ​​to methionine for protein production. A daily intake of 400 mcg of folic acid during the first trimester can reduce neural tube defects by approximately 50%. Folic acid is a methyl group donor, and research indicates that improper methylation can cause neural tube defects. Similarly, a reduction in vitamin B12 or folic acid leads to a buildup of homocysteine, which can inhibit methyl transfer reactions. Vitamin B12 enhances methionine synthesis and increases the ability of folic acid to lower homocysteine ​​levels for normal methyl metabolism. The vitamin is also necessary for the methylation of proteins involved in the synthesis and maintenance of myelin, and vitamin deficiencies can lead to decreased production of the myelin sheath, which is a material necessary for normal nervous system function. Methionine synthase is necessary for the formation of red blood cells, and vitamin B12 deficiency has been linked to the production of abnormally large and irregularly shaped blood cells.