Methylfolate Plus

By directly providing 5-methylfolate, Methylfolate Plus™ may have benefits for those who do not produce enough 5-methylfolate in response to folic acid supplementation. Methylfolate Plus™ provides folate in the active form of (6S)-5-methyltetrahydrofolic acid, glucosamine salt. Methylfolate is a highly absorbable and activated form of folate, which does not require enzymatic conversion to 5-methylfolate in the body. The glucosamine salt form used in Methylfolate Plus™ is more stable than other commonly used forms of methylfolate. Folate deficiency is one of the most common vitamin deficiencies. In individuals with a homozygous (TT) or heterozygous (CT) genetic predisposition, consuming folate-rich foods may not provide the recommended daily intake of folate, thus the need for supplementation. By directly providing 5-methylfolate, Methylfolate PlusTM may have benefits for those who do not produce enough 5-methylfolate in response to folic acid supplementation. Each serving (1/2 tablet) of Methylfolate PlusTM provides 400 mcg of folate as 5-methylfolate, combined with 25 mcg of vitamin B12 as methylcobalamin in our biologically active, phytochemical-rich plant base.