Vitamin D3, K2 and A
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Vitamins K2, D3, and A provide clinically relevant doses of the three fat-soluble vitamins essential for optimal bone health. Although necessary for cardiovascular health, blood sugar regulation, immune function and inflammation control, vitamins A, D3 and K2 have complementary physiological functions related to bones, such as modulation of gene expression in osteoblasts and the carboxylation of osteocalcin, an enzyme necessary for bone formation. This is illustrated by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K2 is added to vitamin D3 supplementation.
Vitamin D3 has diverse and important functions in multiple body systems, and widespread deficiency amplifies these crucial roles. Supplementation is associated with a well-established reduction in osteoporotic fractures. Correcting a vitamin D3 deficiency is essential when supplementing with vitamin A, as vitamin A appears to support bone health if vitamin D3 levels are adequate. Vitamin K2 is now recognized as being necessary not only for clotting, but also for the carboxylation of enzymes essential for healthy bones and blood vessels. Indeed, a meta-analysis showed improved spinal BMD and reduced fractures in postmenopausal women with osteoporosis, while data from controlled trials show reduced age-related BMD decline in healthy postmenopausal women. The MK-7 form of vitamins K2, D3 and A has a longer half-life than any other form.
Adults: 4 drops (0.25 ml) daily or as directed by a healthcare professional.
Medicinal ingredients per dose (4 drops):
Vitamin A (Palmitate) 500 IU (151 mcg RAE)
Vitamin D3 (cholecalciferol) 1,000 IU (25 mcg)
Vitamin K2 (menaquinone-7) (MK-7) (natto bean) 50 mcg
Nonmedicinal ingredients: Medium chain triglycerides, organic flaxseed oil, natural vitamin E (non-GMO sunflower oil), natural vanilla flavor.
You have questions ?
You can reach our team of experts by telephone Monday to Friday from 10 a.m. to 5 p.m. We will be able to help you choose the right product for you.